ОТКРЫТЫЙ КУРС «ИЗБРАННЫЕ ВОПРОСЫ БИОПСИХО­ЛОГИИ»

Является ли человеческое поведение продуктом анатомии мозга и физиологии? Можно ли смотреть на психологию как на биологическую дисциплину? Чем обусловлены психические нарушения? Почему, несмотря на впечатляющий прогресс научного знания в постгеномную эпоху, разработка способов лечения психических болезней остается такой сложной задачей? Возможен ли прорыв в этой области?

Данный курс поможет слушателям лучше разобраться в различных проявлениях психических состояний, понять самих себя и окружающих людей. Особое внимание будет уделено депрессии, страхам, психопатии и склонности к совершению преступлений.

Айла Арслан — молекулярный нейробиолог. После присвоения ей степени магистра в области биотехнологий в Ближневосточном техническом университете (Турция) в 2001 году она получила стипендию Немецкого научно-исследовательского общества (DFG) и смогла написать докторскую диссертацию (Phd) в области молекулярной нейронауки в Гейдельбергском университете (Германия). Она является членом редакционного совета журнала "Journal of Integrative Neuroscience", редактором обзоров "Frontiers in Neuroscience", а в настоящее время, в качестве приглашенного редактора, курирует два специальных выпуска "Journal of Visualized Experiments" (JOVE) и "Journal of Integrative Neuroscience".

Курс проводится на английском языке в формате онлайн с 6 по 30 апреля 2021.

План лекций:

  • Лекция 1: Введение;
  • Лекция 2: Нейронная доктрина;
  • Лекция 3: Нейроанатомия. Часть 1;
  • Лекция 4: Нейроанатомия. Часть 2;
  • Лекция 5: Нейропластичность;
  • Лекция 6: Депрессия;
  • Лекция 7: Нейробиология депрессии;
  • Лекция 8: Тревожный мозг.
    • Лекция 1
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      • Stephens, G. J., Osborne, L. C., & Bialek, W. (2011). Searching for simplicity in the analysis of neurons and behavior. Proceedings of the National Academy of Sciences of the United States of America, 108 Suppl 3(Suppl 3), 15565–15571.
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      • Tryon, R. C. (1940). Genetic differences in maze-learning ability in rats. Yearbook of the National Society for Studies in Education, 39, pp. 111-119.
        Лекция 2

      • Bear M., Connors B,. Paradiso M.A. (2020) Neuroscience: Exploring the Brain, 4th Edition Jones & Bartlett Learning.
      • Gross C. (2013). Some revolutions in neuroscience. Journal of cognitive neuroscience, 25(1), 4–13.
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        Лекция 3

      • Bear M., Connors B,. Paradiso M.A. (2020) Neuroscience: Exploring the Brain, 4th Edition Jones & Bartlett Learning.
        Лекция 4

      • Antonov, I., Antonova, I., Kandel, E. R., & Hawkins, R. D. (2001). The contribution of activity-dependent synaptic plasticity to classical conditioning in Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(16), 6413–6422.
      • Bartsch, T., & Wulff, P. (2015). The hippocampus in aging and disease: From plasticity to vulnerability. Neuroscience, 309, 1–16. https://doi.org/10.1016/j.neuroscience.2015.07.084/
      • Bear M., Connors B,. Paradiso M.A. (2020) Neuroscience: Exploring the Brain, 4th Edition Jones & Bartlett Learning.
      • Bliss TV, Lomo T (July 1973). "Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path". The Journal of Physiology. 232 (2): 331–56.
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      • Squire L. R. (2009). The legacy of patient H.M. for neuroscience. Neuron, 61(1), 6–9.
        Лекция 5

      • Arslan A. (2015). Genes, brains, and behavior: imaging genetics for neuropsychiatric disorders. The Journal of neuropsychiatry and clinical neurosciences, 27(2), 81–92.
      • Arslan A. (2018). Imaging genetics of schizophrenia in the post-GWAS era. Progress in neuro-psychopharmacology & biological psychiatry, 80(Pt B), 155–165.
      • Arslan A. (2018). Mapping the Schizophrenia Genes by Neuroimaging: The Opportunities and the Challenges. International journal of molecular sciences, 19(1), 219.
      • Ayla Arslan (2018) Application of neuroimaging in the diagnosis of depression, -invited author- In: Kim YK (eds). “Understanding Depression- Volume 2. Clinical Manifestations, Diagnosis and Treatment, p69-81 Springer.
      • Russ, T.C., Woelbert, E., Davis, K.A.S. et al. How data science can advance mental health research. Nat Hum Behav 3, 24–32 (2019).
        Лекция 6

      • Arslan A. (2015). Genes, brains, and behavior: imaging genetics for neuropsychiatric disorders. The Journal of neuropsychiatry and clinical neurosciences, 27(2), 81–92.
      • Choate, L. H. & Gintner, G. G. (2011). Prenatal depression: Best practices for diagnosis and treatment. Journal of Counseling and Development, 84, 373-382.
      • Flint, J., & Kendler, K. S. (2014). The Genetics of Major Depression. Neuron, 81(5), 1214.
      • Monteith, S., Glenn, T., Geddes, J. et al. (2015). Big data are coming to psychiatry: a general introduction. Int J Bipolar Disord 3, 21.
      • Russ, T.C., Woelbert, E., Davis, K.A.S. et al. How data science can advance mental health research. Nat Hum Behav 3, 24–32 (2019).
      • Sullivan PF, Agrawal A, Bulik CM, Andreassen OA, Borglum AD, Breen G, Cichon S, Edenberg HJ, Faraone SV, Gelernter J, et al. (2018). Psychiatric Genomics: An Update and an Agenda. Am J Psychiatry 175, 15–27.
      • Unal-Aydin P., Aydin, O., Arslan A. (2021) Genetic architecture of depression: Where do we stand now? Adv Exp Med Biol, Vol. 1305, Yong-Ku Kim (Eds): Major Depressive Disorder, Springer Nature (in press).
        Лекция 7

      • Arslan A, Aydin, PU, Dogan T., Aydin O (2021) Optogenetic animal models of depression: from mouse to man. Yong-Ku Kim (Eds): Translational Research Methods for Major Depressive Disorder, Neuromethods, Springer (In press).
      • Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., & Poulton, R. (2003). Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (New York, N.Y.), 301(5631), 386–389. https://doi.org/10.1126/science.1083968
      • Caspi, A., & Moffitt, T. E. (2006). Gene-environment interactions in psychiatry: joining forces with neuroscience. Nature reviews. Neuroscience, 7(7), 583–590. https://doi.org/10.1038/nrn1925
      • Du, Y., Gao, X. R., Peng, L., & Ge, J. F. (2020). Crosstalk between the microbiota-gut-brain axis and depression. Heliyon, 6(6), e04097.
      • Musci, R. J., Augustinavicius, J. L., & Volk, H. (2019). Gene-Environment Interactions in Psychiatry: Recent Evidence and Clinical Implications. Current psychiatry reports, 21(9), 81. https://doi.org/10.1007/s11920-019-1065-5
      • Sekirov, I., Russell, S. L., Antunes, L. C., & Finlay, B. B. (2010). Gut microbiota in health and disease. Physiological reviews, 90(3), 859–904. https://doi.org/10.1152/physrev.00045.2009
        Лекция 8

      • Balon, R., & Starcevic, V. (2020). Role of Benzodiazepines in Anxiety Disorders. Advances in experimental medicine and biology, 1191, 367–388.
      • Bourin M. (2020). Experimental Anxiety Model for Anxiety Disorders: Relevance to Drug Discovery. Advances in experimental medicine and biology, 1191, 169–184.
      • Craske, M., Stein, M., Eley, T. et al. Anxiety disorders. Nat Rev Dis Primers 3, 17024 (2017).
      • Meuret, A. E., Tunnell, N., & Roque, A. (2020). Anxiety Disorders and Medical Comorbidity: Treatment Implications. Advances in experimental medicine and biology, 1191, 237–261.
      • Park, S. C., & Kim, Y. K. (2020). Anxiety Disorders in the DSM-5: Changes, Controversies, and Future Directions. Advances in experimental medicine and biology, 1191, 187–196. https://doi.org/10.1007/978-981-32-9705-0_12
      • Ströhle, A., Gensichen, J., & Domschke, K. (2018). The Diagnosis and Treatment of Anxiety Disorders. Deutsches Arzteblatt international, 155(37), 611–620.